{"id":1787,"date":"2021-01-21T17:36:53","date_gmt":"2021-01-21T08:36:53","guid":{"rendered":"http:\/\/www.riis.okayama-u.ac.jp\/research_highlights\/1787\/"},"modified":"2022-01-15T22:27:26","modified_gmt":"2022-01-15T13:27:26","slug":"%e3%81%aa%e3%81%9c%e7%a7%81%e3%81%9f%e3%81%a1%e3%81%ae%e8%84%b3%e3%81%af%e5%ad%a6%e7%bf%92%e3%82%84%e8%a8%98%e6%86%b6%e3%82%92%e3%81%99%e3%82%8b%e3%81%93%e3%81%a8%e3%81%8c%e3%81%a7%e3%81%8d%e3%82%8b","status":"publish","type":"research_highlights","link":"https:\/\/www.riis.okayama-u.ac.jp\/ja\/research_highlights\/1787","title":{"rendered":"\u306a\u305c\u79c1\u305f\u3061\u306e\u8133\u306f\u5b66\u7fd2\u3084\u8a18\u61b6\u3092\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u304b\uff5e\u6d77\u99ac\u8208\u596e\u6027\u30b7\u30ca\u30d7\u30b9\u306b\u304a\u3051\u308b\u9577\u671f\u5897\u5f37\/\u9577\u671f\u6291\u5236\u767a\u73fe\u6a5f\u69cb\u306e\u7d71\u4e00\u7684\u7406\u89e3\uff5e"},"content":{"rendered":"<div style=\"margin-bottom: 20px; padding-top: 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style=\"font-style: italic;\">Scientific Reports<\/span>\u300d\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\r\n\u3000\u672c\u7814\u7a76\u6210\u679c\u306f\u3001LTP\u304a\u3088\u3073LTD\u3078\u306e\u95a2\u4e0e\u304c\u7279\u5b9a\u3055\u308c\u3066\u3044\u308b\u30bf\u30f3\u30d1\u30af\u8cea(\u4e26\u3073\u306b\u8907\u5408\u4f53)\u306e\u3001AMPAR\u8f38\u9001\u30b7\u30b9\u30c6\u30e0\u306b\u304a\u3051\u308b\u5f79\u5272\u3084\u3001\uff11\u5206\u5b50\u8a08\u6e2c\u306b\u3088\u3063\u3066\u89b3\u6e2c\u3055\u308c\u3066\u3044\u308b\u3055\u307e\u3056\u307e\u306a\u5074\u9762\u3092\u3001\u5305\u62ec\u7684\u306b\u7406\u89e3\u30fb\u8aac\u660e\u3059\u308b\u305f\u3081\u306e\u5206\u5b50\u57fa\u76e4\u3068\u306a\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\r\n<\/div>\r\n<div style=\"margin-bottom: 50px;\">\r\n<h4>\u25c6\u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8<\/h4>\r\n<ul>\r\n\t<li>\u3053\u308c\u307e\u3067\u3001\u8133\u306e\u5b66\u7fd2\u3084\u8a18\u61b6\u306e\u5f62\u6210\u306b\u95a2\u308f\u308b\u6d77\u99ac\u8208\u596e\u6027\u30b7\u30ca\u30d7\u30b9\u306e\u9577\u671f\u5897\u5f37(LTP)\u3068\u9577\u671f\u6291\u5236(LTD)\u3092\u7d71\u4e00\u7684\u306b\u8aac\u660e\u3059\u308b\u5206\u5b50\u6a5f\u69cb\u306f\u672a\u89e3\u660e\u3067\u3057\u305f\u3002<\/li>\r\n\t<li>\u6d77\u99ac\u8208\u596e\u6027\u30cb\u30e5\u30fc\u30ed\u30f3\u306e\u5f8c\u30b7\u30ca\u30d7\u30b9\u306b\u6d41\u5165\u3059\u308b\u30ab\u30eb\u30b7\u30a6\u30e0\u30a4\u30aa\u30f3\u306e\u591a\u5be1\u306b\u4f9d\u5b58\u3057\u305fAMPA\u578b\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u53d7\u5bb9\u4f53\u306e\u30a8\u30ad\u30bd\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\u3068\u30a8\u30f3\u30c9\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\u306e\u7af6\u5408\u306b\u6ce8\u76ee\u3059\u308b\u3053\u3068\u3067\u3001LTP\u304a\u3088\u3073LTD\u3092\u7d71\u4e00\u7684\u306b\u7406\u89e3\u3067\u304d\u308b\u3053\u3068\u3092\u5927\u898f\u6a21\u6570\u7406\u30e2\u30c7\u30eb\u30b7\u30df\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u306b\u3088\u308a\u5b9f\u8a3c\u3057\u307e\u3057\u305f\u3002<\/li>\r\n<\/ul>\r\n<\/div>\r\n<div style=\"width: 400px;\">\r\n<figure><img decoding=\"async\" src=\"http:\/\/www.riis.okayama-u.ac.jp\/wp-content\/uploads\/2021\/01\/758_image_1.jpg\" alt=\"\" width=\"400\" class=\"aligncenter\" \/>\r\n<figcaption>\u56f31. \u6d77\u99ac\u8208\u596e\u6027\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u304a\u3051\u308bLTP\/LTD\u3092\u518d\u73fe\u3059\u308b\u5f8c\u30b7\u30ca\u30d7\u30b9\u306b\u304a\u3051\u308bAMPAR\u8f38\u9001\u30b7\u30b9\u30c6\u30e0\u3002<\/figcaption>\r\n<\/figure>\r\n<br \/>\r\n<figure><img decoding=\"async\" src=\"http:\/\/www.riis.okayama-u.ac.jp\/wp-content\/uploads\/2021\/01\/758_image_2.jpg\" alt=\"\" width=\"400\" class=\"aligncenter\" \/>\r\n<figcaption>\u56f32. (\u5de6) \u57fa\u5e95\u72b6\u614b\u306b\u304a\u3051\u308b\u30b7\u30ca\u30d7\u30b9\u306e\u6a21\u5f0f\u56f3\u3002(\u53f3\u4e0b) LTP\u304a\u3088\u3073LTD\u523a\u6fc0\u306b\u5fdc\u3058\u305f\u3001\u30b7\u30ca\u30d7\u30b9\u5f8c\u819c\u4e0a\u3067\u306eAMPAR\u6570\u306e\u6642\u9593\u5909\u5316\u3002<\/figcaption>\r\n<\/figure>\r\n<\/div>\r\n<div style=\"margin-top: 50px;\">\u25a0\u8ad6\u6587\u60c5\u5831<br \/>\r\n\u8ad6 \u6587 \u540d\uff1aMechanism underlying hippocampal long-term potentiation and depression based on competition between endocytosis and exocytosis of AMPA receptors<br \/>\r\n\u63b2 \u8f09 \u7d19\uff1a<span style=\"font-style: italic;\">Scientific Reports<\/span><br \/>\r\n\u8457 \u3000\u8005\uff1aTomonari Sumi, Kouji Harada<br \/>\r\nD O I\uff1a10.1038\/s41598-020-71528-3<br \/>\r\nU R L\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41598-020-71528-3\" rel=\"noopener noreferrer\" target=\"_blank\">https:\/\/www.nature.com\/articles\/s41598-020-71528-3<\/a><\/div>\r\n<div style=\"margin-top: 50px;\">\r\n<p>\uff1c\u8a73\u3057\u3044\u7814\u7a76\u5185\u5bb9\u306b\u3064\u3044\u3066\uff1e<\/p>\r\n<ul>\r\n\t<li><a href=\"https:\/\/www.okayama-u.ac.jp\/up_load_files\/press_r2\/press20200907.pdf\" rel=\"noopener noreferrer\" target=\"_blank\">\u306a\u305c\u79c1\u305f\u3061\u306e\u8133\u306f\u5b66\u7fd2\u3084\u8a18\u61b6\u3092\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u304b\uff5e\u6d77\u99ac\u8208\u596e\u6027\u30b7\u30ca\u30d7\u30b9\u306b\u304a\u3051\u308b\u9577\u671f\u5897\u5f37\/\u9577\u671f\u6291\u5236\u767a\u73fe\u6a5f\u69cb\u306e\u7d71\u4e00\u7684\u7406\u89e3\uff5e<\/a><\/li>\r\n\t<li>\r\n<p><a href=\"https:\/\/www.okayama-u.ac.jp\/tp\/release\/release_id758.html\" rel=\"noopener noreferrer\" target=\"_blank\">\u5ca1\u5c71\u5927\u5b66\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9<\/a><\/p>\r\n<\/li>\r\n\t<li>\r\n<p><a href=\"http:\/\/phys.chem.okayama-u.ac.jp\/\" rel=\"noopener noreferrer\" target=\"_blank\">\u7406\u8ad6\u7269\u7406\u5316\u5b66\u7814\u7a76\u5ba4<\/a><\/p>\r\n<\/li>\r\n<\/ul>\r\n<\/div>\r\n<div>\r\n<p>\u306a\u304a\uff0c\u672c\u7814\u7a76\u306e\u8a18\u4e8b\u306f\uff0c\u79d1\u5b66\u65b0\u805e\u3067\u7d39\u4ecb\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\r\n<figure><img decoding=\"async\" src=\"http:\/\/www.riis.okayama-u.ac.jp\/wp-content\/uploads\/2021\/01\/science_news20201002.jpg\" alt=\"\" width=\"400\" class=\"aligncenter\" \/>\r\n<figcaption>\u79d1\u5b66\u65b0\u805e\uff12\uff10\uff12\uff10\u5e74\uff11\uff10\u6708\uff12\u65e5\u63b2\u8f09\u8a18\u4e8b<\/figcaption>\r\n<figcaption>\u79d1\u5b66\u65b0\u805e\u793e\u306e\u8a31\u53ef\u3092\u5f97\u3066\u63b2\u8f09\u3057\u3066\u304a\u308a\u307e\u3059\u3002\u8ee2\u8f09\u306f\u3054\u9060\u616e\u304f\u3060\u3055\u3044<\/figcaption>\r\n<\/figure>\r\n<\/div>\r\n<p>&nbsp;<\/p>\r\n<div>\r\n<p>\uff1c\u304a\u554f\u3044\u5408\u308f\u305b\uff1e<br \/>\r\n\u7570\u5206\u91ce\u57fa\u790e\u79d1\u5b66\u7814\u7a76\u6240<br \/>\r\n\u51c6\u6559\u6388\u3000\u58a8\u3000\u667a\u6210\uff08\u3059\u307f\u3000\u3068\u3082\u306a\u308a\uff09<br \/>\r\n\uff08\u96fb\u8a71\u756a\u53f7\uff09086-251-7837<\/p>\r\n<\/div>","protected":false},"author":12,"featured_media":1964,"template":"","research_highlights_cat":[55],"class_list":["post-1787","research_highlights","type-research_highlights","status-publish","has-post-thumbnail","hentry","research_highlights_cat-highlights-y2021"],"scholar_watch_public_preview":null,"scholar_watch_wpml":{"language":"ja","trid":5030,"translations":{"ja":1787}},"acf":[],"_links":{"self":[{"href":"https:\/\/www.riis.okayama-u.ac.jp\/ja\/wp-json\/wp\/v2\/research_highlights\/1787","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.riis.okayama-u.ac.jp\/ja\/wp-json\/wp\/v2\/research_highlights"}],"about":[{"href":"https:\/\/www.riis.okayama-u.ac.jp\/ja\/wp-json\/wp\/v2\/types\/research_highlights"}],"author":[{"embeddable":true,"href":"https:\/\/www.riis.okayama-u.ac.jp\/ja\/wp-json\/wp\/v2\/users\/12"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.riis.okayama-u.ac.jp\/ja\/wp-json\/wp\/v2\/media\/1964"}],"wp:attachment":[{"href":"https:\/\/www.riis.okayama-u.ac.jp\/ja\/wp-json\/wp\/v2\/media?parent=1787"}],"wp:term":[{"taxonomy":"research_highlights_cat","embeddable":true,"href":"https:\/\/www.riis.okayama-u.ac.jp\/ja\/wp-json\/wp\/v2\/research_highlights_cat?post=1787"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}